To make matters worse, offensive lineman Spencer Burford, who was supposed to start at left tackle with Williams and his backup Jaylon Moore on IR for the season, is listed as ‘out’ on the injury report with a calf injury he sustained in the team’s Week 16 loss to the Miami Dolphins.

The bad injury situation exacerbated for the 49ers during the week with multiple downgrades – Colton McKivitz, Charvarius Ward, and Ji’Ayir Brown. Two of those are starting secondary players which would hamper the 49er pass defense. Meanwhile, the Lions got an upgrade with Terrion Arnold.

With the San Francisco 49ers looking to play spoiler on Monday Night Football against the Detroit Lions, it appears they’ll have Isaac Guerendo back on the field. The 49ers’ rookie running back looks to return to the field after working through hamstring and foot injuries that caused him to miss Week 16,

With nothing left to play for this season, the 49ers will have to hope that Brock Purdy grows from a challenging 2024 campaign.

T he San Francisco 49ers season has not gone the way they had hoped. Injuries, underperformance, bad luck, and some questionable late-game decisions have led them to a 6-9 record