The genome is more than a linear code; it is a dynamic structure whose three-dimensional folding dictates how genes are regulated. Traditional sequencing technologies capture base-level variation but ...

A team of researchers has generated one of the most detailed 3D maps of human chromosomes, cataloging over 140,000 DNA looping interactions.

New work from UC Davis and the University of Utah shows how the 3D structure of DNA inside a germ cell commits it to develop into a sperm cell. The discovery could improve understanding of fertility ...

New 3D genome maps reveal how DNA folding controls gene activity, offering fresh clues into disease and cell function.

One of the most detailed 3D maps of how the human chromosomes are organized and folded within a cell's nucleus is published ...

DNA isn't just a long string of genetic code, but an intricate 3D structure folded inside each cell. That means the tools used to study DNA need to be just as sophisticated-able to read not only the ...

Researchers created the most detailed maps yet of the genome’s three-dimensional organization using human stem cells and ...

A robust platform for analyzing 3D genome architecture and epigenomic features enables a deeper understanding of gene regulation in specific cell types. Researchers analyze various aspects of gene ...

Marvel at the tiny nanoscale structures emerging from research labs at Duke University and Arizona State University, and it's easy to imagine you're browsing a catalog of the world's smallest pottery.

A new approach breaks down complicated designs into modular building blocks for easy assembly from the bottom up. (Nanowerk News) When the Empire State Building was constructed, its 102 stories rose ...