When asthma is severe and long term, it becomes less amenable to treatment -- or less "reversible." This process, remodeling of the airways with peribronchial fibrosis, has been widely attributed to ...

Today, there is a broader understanding of asthma, including the genetic, environmental, and host-related factors that contribute to declining lung function in patients. Asthma affects up to 13% of ...

Asthma is a common chronic respiratory condition, characterized, clinically, by an excessive tendency toward airway narrowing and, pathologically, by structural changes in the airway, termed as ...

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Shortness of breath that persists weeks after the cough has resolved may be a sign that the airway has not fully recovered. Below, we examine how continued breathlessness can ...

Airway remodeling in asthma describes the structural alterations of the bronchial wall that accompany chronic inflammation, including smooth muscle hypertrophy, subepithelial fibrosis and increased ...

Individuals with chronic asthma show a progressive decline in lung function that is thought to be due to structural remodeling of the airways characterized by subepithelial fibrosis and smooth muscle ...

Please provide your email address to receive an email when new articles are posted on . Airways with mucus plugs have thicker epithelium, basement membranes and smooth muscle than unplugged airways.

Editor’s note: An analysis of reports of randomized trials for improbable distributions of baseline data included 934 reports published in the Journal and identified 11 with distributions of baseline ...

The US Treasury on Tuesday announced new sanctions targeting an alleged fuel smuggling ring that benefits the notorious Jalisco New Generation Cartel in neighboring Mexico.The new sanctions target two ...

This is an excellent question, and one for which we do not have a definitive answer. There is some experimental evidence in animal studies to suggest that use of ICS, combined with allergen avoidance, ...

To the Editor: The article by Grainge and coworkers (May 26 issue) 1 suggests that mechanical stress leads to airway remodeling in asthma. If this is the case, why were the remodeling outcomes the ...