A team of researchers at Baylor College of Medicine, UMass Chan Medical School and Cincinnati Children's Hospital Medical Center has developed a new treatment that could change the outlook for ...

Pooled phase 3 data presented at North American Society for Pediatric Gastroenterology, Hepatology & Nutrition 2023 support the benefit-risk profile of the ileal bile acid transport inhibitor in ...

Amber Selvey spoke exclusively with PEOPLE about the deaths of her husband, Jason, and their son, Daniel, six years apart Both hda Alagille Syndrome, a genetic condition that can cause liver damage, ...

Alagille syndrome, a genetic disease estimated to affect 1 in 30,000 individuals, is caused by mutations in the gene JAG1 in most cases. The mutations affect multiple organs including the liver where ...

An Ipsen drug developed to treat the severe itching that accompanies certain liver disorders is now FDA approved for treating this complication in patients with Alagille syndrome. It’s the second ...

Alagille syndrome is a rare multisystem disorder that primarily affects the liver, heart, and kidneys, and is most frequently associated with pathogenic mutations in the JAG1 gene, with a smaller ...

Credit: Getty Images. Bylvay is an ileal bile acid transporter inhibitor. The Food and Drug Administration (FDA) has approved Bylvay ® (odevixibat) for the treatment of cholestatic pruritus in ...

A woman in England is attempting to raise awareness of a rare illness following the deaths of her husband and son six years apart. While speaking exclusively with PEOPLE, Amber Selvey revealed there ...

Positive opinion from Committee for Medicinal Products for Human Use recommending approval of Bylvay ® (odevixibat) based on Phase III ASSERT clinical-trial data in Alagille syndrome (ALGS) already ...

A drug to treat severe itching in patients with Alagille syndrome should be granted a marketing authorization in the European Union under what the European Medicines Agency (EMA) termed exceptional ...

Event-Free Survival Data from Mirum’s LIVMARLI Alagille Syndrome Program Published in Hepatology Improvement in pruritus, serum bile acid levels and bilirubin were highly predictive of six-year ...