Please provide your email address to receive an email when new articles are posted on . Click here to read the Cover Story, “After decades with only one option, new therapies emerge for congenial ...

Steroid biosynthesis is affected in the AR disorder known as congenital adrenal hyperplasia (CAH): the majority of cases are due to 21-hydroxylase deficiency. Androgen excess affects women’s ...

Hormonal measurements and HLA genotyping of amniotic fluid at midgestation correctly predicted the postnatal dx of CAH in 26 of 29 fetuses at risk for CAH. Of these 26, 6 were predicted to have ...

- CAHtalyst™ Adult Phase 3 Study Met Primary and Important Key Secondary Endpoints, with Crinecerfont Treatment Decreasing Androstenedione Levels and Enabling Glucocorticoid Dose Reduction While ...

New CAHtalyst™ Pediatric and CAHtalyst™ Adult Phase 3 Clinical Study Data in Congenital Adrenal Hyperplasia CAHtalog™ Registry Data Highlighting Impact of Supraphysiologic Glucocorticoid Dosing Phase ...

CAHtalyst™ Met Primary Endpoint Demonstrating a Statistically Significant Decrease from Baseline Daily Glucocorticoid Dose with Androgen Control Key Secondary Endpoint Achieved Statistically ...

The traditional view of nonclassic congenital adrenal hyperplasia is that affected individuals are not glucocorticoid-deficient. The results of a French study now cast doubts on this assumption, ...

SAN DIEGO, Jan. 21, 2025 /PRNewswire/ -- Neurocrine Biosciences, Inc. (Nasdaq: NBIX) today announced publication of a classic congenital adrenal hyperplasia (CAH)-focused supplement in The Journal of ...

Crenessity is expected to be available commercially in approximately 1 week through PANTHERx Rare, a specialty pharmacy. The Food and Drug Administration (FDA) has approved Crenessity TM (crinecerfont ...

Neurocrine Biosciences Inc (NASDAQ:NBIX) announced positive topline data from the Phase 3 CAHtalyst Adult Study evaluating crinecerfont in adults with classic congenital adrenal hyperplasia (CAH) due ...

New, Clinical, genetic, and structural basis of congenital adrenal hyperplasia due to 11β-hydroxylase deficiency, Proceedings of the National Academy of Sciences of the United States of America, Vol.

A complete clinical and genetic profile of a rare inherited disorder, steroid 11-hydroxylase deficiency, which can cause genital masculinization in females, is being reported by an international group ...