New research has identified the specific biological mechanism behind the muscle dysfunction found in myotonic dystrophy type 1 (DM1) and further shows that calcium channel blockers can reverse these ...

Ibutilide is the only Food and Drug Administration-approved intravenous drug for the rapid termination of atrial fibrillation and flutter. Its mechanism of action is undecided. The drug has been ...

An atomic level analysis has revealed how two classes of calcium channel blockers, widely prescribed for heart disease patients, produce separate therapeutic effects through their actions at different ...

Zalicus Initiates the First of Two Phase 2a Studies with Z160, a First-in-Class, Oral, State-Dependent, Selective N-type Calcium Channel Blocker, for the Treatment of Chronic Neuropathic Pain (NASDAQ: ...

CAMBRIDGE, Mass.--(BUSINESS WIRE)--Zalicus Inc. (Nasdaq Capital Market: ZLCS) today announced that preclinical data highlighting its novel, oral ion channel programs for the treatment of pain ...

New research has identified the specific biological mechanism behind the muscle dysfunction found in myotonic dystrophy type 1 (DM1) and further shows that calcium channel blockers can reverse these ...

When you have atrial fibrillation, the two upper chambers of your heart (atria) don't beat in sync with the two lower chambers (ventricles). This makes your heart beat out of rhythm and sometimes very ...

Rate-Control Tx for A-fib: Beta Blockers vs. Calcium Channel Blockers Evidence comparing the effectiveness of beta-blockers (BBs) and calcium channel blockers (CCBs) as first-line rate-control therapy ...

Researchers have found that amlodipine, a calcium-channel blocker prescribed to tens of millions of people for high blood ...

Chicago, IL - A new analysis of data from the Women's Health Initiative Observational Study shows that among the more than 30 000 women with uncomplicated hypertension in this cohort, treatment with ...

Long-term use of a calcium-channel blocker to treat hypertension (high blood pressure) is associated with higher breast cancer risk, according to a report published by JAMA Internal Medicine, a JAMA ...