The team worked for 10 years to uncover the hidden brain-cell death process fueling several dementias, revealing a key new ...

Cell death in dementia has long posed a frustrating problem. Toxic proteins pile up inside neurons in Alzheimer’s disease and ...

While early in life, the accumulation of iron appears to have little effect on neuron function, later in life, it can ...

Caspases are evolutionarily conserved cysteine proteases that cleave their substrates at specific aspartic acid residues, playing a central role in programmed cell death (PCD) 1. These enzymes are ...

Neurodegenerative diseases affect tens of millions of people worldwide. Among these, Alzheimer's and Parkinson's diseases are the most common; in the United States alone, the Alzheimer's Disease ...

Scientists discover karyoptosis, a new cell death mechanism causing nuclear disintegration in Alzheimer's and frontotemporal ...

Researchers at King’s College London and the UK Dementia Research Institute have published new research uncovering a ...

Programmed cell death serves as a critical defense mechanism during viral infection. The kinases RIPK1 and RIPK3, central regulators of programmed cell death pathways, undergo precise modulation ...

Taking ROS as the core node connecting cell death pathways and therapeutic strategies Exploring innovative therapeutic strategies targeting the ROS-cell death network, providing a new direction for ...

Neurodegenerative diseases affect tens of millions of people worldwide. Among these, Alzheimer's and Parkinson's diseases are the most common; in the United States alone, the Alzheimer's Disease ...

Traditional cancer treatments like chemotherapy and radiotherapy can induce immunogenic cell death (ICD), but their efficacy ...