Researchers from Johns Hopkins University and the University of Copenhagen analyzed over 139,000 embryos and identified variants in key meiosis genes, such as SMC1B, that influence chromosomal ...
Chromosomal instability plays a crucial role in the progression of cancer: it shapes the properties of tumor cells and drives the development of therapy resistance. Scientists used state-of-the-art ...
Researchers have revealed the mechanisms by which cells enter senescence because of an imbalance in the number of chromosomes. Chromosomal instability is a common trait in most solid tumors, such as ...
Changes in genes have been linked to the development of different diseases for a while. However, it's not exactly clear what ...
Translocations, in genetics, happen when chromosomes break and the pieces attach to other chromosomes. This mixing of genetic material has important results. The resultant chromosomes are lacking in ...
Researchers who presented their work at the Fertility 2026 conference in Edinburgh, Scotland, say they have identified how ...
I still recall my disappointment one day in 2015. I received the tumor DNA sequencing results for one of my patients, whose cancer had spread from her lungs to her brain. I saw not a single genetic ...
A new discovery by researchers at the RIKEN Center for Biosystems Dynamics (BDR) in Japan upends decades of assumptions regarding DNA replication. Led by Ichiro Hiratani and colleagues, the ...
Boutaina Belkady, Lamiae Elkhattabi, Zouhair Elkarhat, Latifa Zarouf, Lunda Razoki, Jamila Aboulfaraj, Sanaa Nassereddine, Rachida Cadi, Hassan Rouba and Abdelhamid Barakat Background: Intellectual ...