Reducing food intake by 30% reduced the accumulation of DNA mutations—a mouse study finds a new relationship between 'calorie restriction and aging'

"Reducing the amount you eat helps you live longer." Many people have probably heard that before. In fact, previous studies have reported that in animals, including mice, significantly restricting ...
Tech Times on MSN

AlphaGenome Atlas scores all 9 billion DNA mutations, doubles rare-disease hit rate

AlphaGenome Atlas, Google DeepMind's new 1-petabyte genomics database, pre-computes predicted molecular effects for all 9 ...

Google DeepMind publishes AI-powered predictions for the effect of all 9 billion possible single-point mutations in the human genome

Atlas, DeepMind's comprehensive catalogue of predicted DNA mutation effects, could help scientists unlock the cause of rare ...
News Medical

HiDEF-seq technique reveals the origins of DNA mutations in single strands

Mutations are changes in the molecular "letters" that make up the DNA code, the blueprint for all living cells. Some of these changes can have little effect, but others can lead to diseases, including ...
Science Daily

DNA damage can last unrepaired for years, changing our view of mutations

While most known types of DNA damage are fixed by our cells' in-house DNA repair mechanisms, some forms of DNA damage evade repair and can persist for many years, new research shows. This means that ...

Prime assembly can correct multiple mutations at once, pointing toward universal gene therapies

Genomic editing holds great potential yet continues to have limitations. Current methods either rely on untargeted gene ...
Medical Xpress

Researchers discover DNA mechanism that regulates how disease-causing mutations are inherited

University of Queensland researchers have discovered a mechanism in DNA that regulates how disease-causing mutations are inherited. The research paper has been published in Cell Metabolism. Dr. Anne ...
Harvard Medical School

New Gene-Editing Method, ‘Prime Assembly,’ Corrects Multiple Mutations at Once

Approach builds on prime editing, advances journey toward universal gene therapies ...
Labroots

A 'Junk DNA' Mutation That Prevents a Disease

Only around two percent of the human genome codes for proteins, and while those proteins carry out many important functions of the cell, the rest of the genome cannot be ignored. However, for decades ...
Science Daily

Mutations in noncoding DNA become functional in some cancer-driving genes

Despite progress in defining functional elements of noncoding DNA, it is still not fully understood. Researchers, using an experiment that elucidated the function of tens of thousands of noncoding ...