New research has discovered that the molecular machines responsible for copying our DNA have a surprising hidden talent: an ability to create entirely new and highly sophisticated DNA sequences from ...

Genetic information encoded in DNA sequences is a defining feature of all life on Earth. It provides the instructions that cells require to synthesize and assemble their molecular machinery, encodes ...

Translesion synthesis polymerases efficiently incorporate nucleotides opposite DNA lesions. Pol ι, for example, bypasses minor-groove and exocyclic purine adducts. Conventional X-ray crystallography ...

Synthetic polymers play a crucial role in cell biology, serving as delivery vehicles for DNA and drugs, acting as fluorescent probes for cellular sensing, functioning as bioinks for tissue engineering ...

Before a cell divides, its DNA is replicated so that each daughter cell inherits the same genetic information. The two copies, known as "sister chromatids," are held together by a ring-shaped protein ...