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eIF5A inhibition influences T cell dynamics in the pancreatic microenvironment of the humanized mouse model of Type 1 Diabetes. Scientific Reports, 2019; 9 (1) DOI: 10.1038/s41598-018-38341-5; ...
Scientists from the NIH have developed a mouse model of type 2 diabetes. Type 2 diabetes is a common endocrinological disorder that affects between six and ten percent of the Western world. As ...
A pretreatment step could help transplanted pancreatic islets survive longer in patients with type 1 diabetes, according to a ...
The nonobese diabetic mouse as a model of autoimmune diabetes - immune dysregulation gets the NOD. Immunity 7 , 727–738 (1997). Article CAS Google Scholar ...
Finding new treatments or a cure for type I diabetes has been elusive in part because scientists have not had a reliable animal model that mimics the full scope of human type I diabetes. A ...
A Coxsackievirus B vaccine protects against virus-induced diabetes in an experimental mouse model of type 1 diabetes. Diabetologia , 2017; DOI: 10.1007/s00125-017-4492-z Cite This Page : ...
Researchers have seen inflammation in the islets in people with type 2 diabetes, but in Bilal Omar's view, it is only with the new mouse model that it can really be confirmed.
An engineered protein turns off the kind of immune cells most likely to damage tissue as part of type-1 diabetes, hepatitis, ...
These drugs, which mimic the gut hormone glucagon-like peptide-1 (GLP-1), can help treat those with type 2 diabetes by stimulating the production of insulin and improving the function of beta cells.
At right, there are far fewer insulin-producing cells in an islet from a mouse carrying the mutation that causes neonatal diabetes. Credit: Molecular Metabolism (2025). DOI: 10.1016/j.molmet.2025. ...
While not as dramatic as beta-cell TXNIP knockouts, the alpha-cell knockout improved diabetes-associated hyperglycemia and hyperglucagonemia in a mouse model of streptozotocin-induced diabetes.
People with diabetes are more prone to developing Staphylococcus aureus, ... The researchers brought their labs together to conduct a study with antibiotics in a diabetic mouse model of the Staph ...