Parkinson's disease, a common neurodegenerative ailment, affects roughly 1 % of the population aged 60 and up, and the number of cases is anticipated to quadruple by 2040, posing a significant ...

The scientists showed they could precisely interrupt the flow of the differentiation process, thereby enhancing antitumor efficacy. "T cells are the cornerstone of tumor immunotherapy, and we found a ...

As stem cells decide who they want to become, they embark on a journey of gradual differentiation into their final cell fate. This transformation is traditionally depicted by the Waddington landscape ...

Researchers from the University of Toronto (Canada) have presented a new high-resolution gene expression atlas that shows the normal differentiation process of hematopoietic cells at the American ...

Glucose is life's main energy source. But a new study reveals a surprising role as a master manipulator of tissue maturation, hinting at its importance in diabetes and cancer. The sugar glucose, which ...

As cells mature and differentiate (right), they use a much more elaborate and cell-type specific ‘switchboard’ to control their gene expression, especially when compared to earlier, immature stages ...

When you were first conceived, you were a single cell. From this basic fact, we can extrapolate a few things, most especially that all the cells that make up your body today came (indirectly) from ...

(L to R) Co-first authors Peipei Zhou, Ph.D., Hao Shi, Ph.D. and corresponding author Hongbo Chi, Ph.D., all of the St. Jude Department of Immunology. T cells are used in adoptive cell therapy (ACT) ...