Hirschsprung disease is a potentially fatal birth defect in which the enteric nervous system (ENS) is missing from the distal bowel Hirschsprung disease is defined by the absence of enteric neurons at ...

A manometric technic is described for the diagnosis of Hirschsprung's disease without the necessity of deep-muscle rectal biopsy. Separate pressure recordings were obtained from the internal and ...

Scientists at the University of Michigan Medical School have identified defective stem cells as the key to a serious, sometimes life-threatening, intestinal disorder called Hirschsprung's disease, ...

A new study has demonstrated the potential of stem cell therapy to treat those with Hirschsprung disease. A new study led by researchers at UCL and the University of Sheffield, has demonstrated the ...

Hirschsprung’s disease, or congenital aganglionosis, is a developmental disorder of the enteric nervous system and is the most common cause of intestinal obstruction in neonates and infants. The ...

Hirschsprung disease and meconium ileus both disrupt bowel movements and can require urgent medical attention. The two conditions have different causes and treatments. Hirschsprung disease happens ...

Ankush Gosain, MD, PhD, of Le Bonheur Children's Hospital and the University of Tennessee Health Science Center has focused his research on determining the mechanisms underlying abnormal development ...

Treatment for Hirschsprung disease typically involves a surgical procedure known as a pull-through procedure to remove a section of the colon. Some people may also need ostomy surgery. Hirschsprung ...

When a newborn is unable to pass stool, the cause could be Hirschsprung’s Disease, a rare congenital disorder that can lead to serious complications. Dr. Michael Rollins explains the disease and how ...