Nicotine and its byproducts may stay in your body for hours, days, or longer, depending on how often you've used nicotine and other individual factors.

Nicotine's effects (and how long they last) depend on many variables Medically reviewed by Armeen Poor, MD Nicotine stays in your body for different amounts of time depending on the type of test.

Whether you're smoking cigarettes or vaping e-cigarettes, you're ingesting nicotine. Either way, the addictive substance is linked to a host of health issues, and experts say they still don't have a ...