Researchers from The University of Texas at Dallas' Center for Advanced Pain Studies (CAPS) and their colleagues have made a fundamental discovery about a key mechanism that enables nervous system ...

Loss of synapses and synapse function sit at the heart of a number of diseases, not just neurodegenerative examples such as dementia and Parkinson's disease but also conditions such as diabetes. We do ...

Synapse labeling strategies involve marking synaptic contact sites with different fluorescent proteins in the pre- and postsynaptic compartments. The interface between these contacts is also labeled, ...

This original animation illustrates that presynaptic neurons secrete VLK, which then phosphorylates the extracellular side of ephrin type-B receptor 2 (EphB2) extruding from the membranes of ...