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Tiny human heart organoids open the door to safer, faster drug discovery
Millions of people live with atrial fibrillation, a racing, uneven heartbeat that can leave you exhausted and scared. Yet it ...
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Specific human gene can help the heart repair itself from heart attack or heart failure
A naturally occurring gene called Cyclin A2 (CCNA2), which turns off after birth in humans, can actually make new, functioning heart cells and help the heart repair itself from injury, including a ...
A study led by Maria Carmo-Fonseca at GIMM has helped clarify one of the main limitations of lab-grown heart cells, which are ...
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Magnetic torque boosts cardiac organoid maturation, mimicking heart development
Heart disease remains the leading cause of death worldwide, yet progress in understanding and treating cardiac disorders is ...
Reintroduction of the Cyclin A2 gene enables adult human cardiomyocytes to divide, producing functional daughter cells and promoting heart repair. The therapy uses a replication-deficient adenoviral ...
University of Cambridge scientists have used human stem cells to create three-dimensional embryo-like structures that replicate certain aspects of very early human development - including the ...
Type 2 diabetes doesn’t just raise the risk of heart disease—it physically reshapes the heart itself. Researchers studying ...
Heart disease is the top cause of death in the United States, resulting in one in three deaths in 2023. In addition to being such a vital organ, the adult heart, unlike other parts of the body, cannot ...
You probably know someone who is affected by cancer. This disease results when cells divide uncontrollably and can make a person sick, sometimes very seriously. I’m a biologist who specializes in the ...
From left to right - the cell in the initial frame is from a 55-year-old donor heart. The next image shows the cell rounding up after receiving Cyclin A2 and the cell division takes place shortly ...
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