“You’re on a chemotherapeutic and your oncologist may say that your dosage is X, while a nephrologist is telling you that the proximal tubules in your kidneys can’t handle it. You’re harming them.” ...
In the lab, it's easier to grow simple balls of cells than complex asymmetrical structures with two distinct ends—like the one million filtering units—nephrons—that make up a human kidney. But new ...
Scientists at the University of Southern California have engineered synthetic organiser cells that produce localised Wnt ...
Synthetic organizers provide a way to control formation of kidney organoids as more reliable models for studying disease and ...
In a study published in Science, USC researchers paired a biological discovery with an engineering feat to create more ...
A group of essential signaling molecules known as the Wnt pathway emerged early in the evolution of multicellular life. Scientists have been studying Wnt actions for four decades to comprehend its ...
The kidney, a critical organ for waste filtration and fluid regulation, is the subject of a groundbreaking molecular mapping project that could reshape our understanding of renal health. Despite ...
In a study published in Science, USC researchers paired a biological discovery with an engineering feat to create more faithful, reproducible ...
A pair of USC Stem Cell mouse studies detail how progenitor cells self-renew, differentiate, and aggregate into early kidney structures, offering insights for the creation of stem cell-based ...
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