Insulin resistance is concomitant with type 2 diabetes, obesity, hypertension, and other features of the metabolic syndrome. Because insulin resistance is associated with cardiovascular disease, both ...

Researchers from the German Diabetes Center (DDZ) and the Heinrich Heine University Düsseldorf (HHU) have studied the temporal pattern of insulin action on protein kinases in human muscle cells in ...

The common forms of type 2 diabetes are caused by a constellation of genetic and epigenetic factors and molecular changes related to diet; lifestyle, including lack of exercise and sleep; ...

Research from the Max Planck Florida Institute for Neuroscience has identified a mechanism through which insulin-like growth factors facilitate brain plasticity. The insulin superfamily of hormones, ...

In a discovery that may further the understanding of diabetes and human longevity, scientists at Scripps Research have found a new biological mechanism of insulin signaling. Their study, involving the ...

The Primary Oral Insulin Trial (POInT) investigates whether type 1 diabetes in at-risk children can be prevented through oral ...

Tirzepatide is a recently approved treatment for type-2 diabetes. Treatment with tirzepatide decreases body weight while improving glucose metabolism in patients with obesity and type-2 diabetes.

Taken together, our experimental paradigm in endothelial cells and VSMCs indicates that under normal conditions insulin is antiatherogenic. In endothelial cells, insulin stimulates NO production and ...