Proteins responsible for the pumping force of the heart beat and muscle cell contraction appear to cluster together in intercalated discs in an extremely organized fashion. Scientists from the NYU ...

The intercalated discs that connect cardiomyocytes control cell-to-cell adhesion and communication. Several macromolecular structures (desmosomes, fascia adherens junctions, gap junctions, and ...

Adhesion between cardiac myocytes is essential for the heart to function as an electromechanical syncytium. Although cell-matrix and cell-cell adhesions reorganize during development and disease, the ...

Diseased hearts may be thrown out of rhythm by structural differences -- now visible for the first time -- in protein groups that connect heart muscle cells, according to the authors of a study to be ...