Until now, doctors knew hepatic stellate cells mainly as drivers of liver fibrosis. The actual functions of this cell type have hardly been studied to date. Researchers have now determined that ...

Histology was classified according to METAVIR ... with comparable diagnostic accuracy for the non-invasive staging of liver fibrosis. Serum tests are informative in a higher proportion of patients ...

Investigators have found that the gene Asah1 plays a crucial protective role in preventing the progression of nonalcoholic ...

Metabolic dysfunction-associated steatohepatitis (MASH) is a polygenic disorder influenced by multiple genes, but their ...

However, in 13.4% of patients, liver histology was unchanged - one had mild steatosis and one had cirrhosis. In one patient (6.7%), progression from mild steatosis to pericellular fibrosis was ...

The study demonstrates that pharmacological administration of FGF21 protects against MASH pathology at least ... therapeutic potential for treating liver fibrosis and MASH. More information ...

Reported unprecedented, statistically significant reversal of compensated cirrhosis (F4) due to MASH after 96 weeks of treatment with ...