Multiple system atrophy (MSA) refers to a group of progressive neurodegenerative disorders that affects the basal ganglia and the motor system (parkinsonism), autonomic nervous system (dysautonomia ...

The diagnosis of MSA can be challenging because its initial symptoms resemble those of other diseases. MSA can only be conclusively diagnosed through examination of the brain and nervous system. A ...

Multiple system atrophy — whose worldwide awareness day is commemorated every Oct. 3 — includes disorders that historically had been referred to as Shy-Drager syndrome, olivopontocerebellar ...

MSA causes gradual progressive damage to the nerve cells in the brain and spinal cord. People with MSA do not always have a positive outlook and often live for 6–9 years after their symptoms begin.

Dear Dr. Donohue: I have a friend, age 56, who is diagnosed with multiple system atrophy. His doctor says he has a life expectancy of four to nine years. My friend thinks he’ll die in six months.

Multiple system atrophy (MSA) is a progressive neurodegenerative disease of undetermined aetiology, which affects both sexes 1 with a prevalence ranging between 2.3 and 4.9 per 100 000 in various ...

Infantile spinal muscular atrophy: Symptoms, outlook, and support Medically reviewed by Avi Varma, MD, MPH, AAHIVS, FAAFP — Written by Kristina Iavarone on January 12, 2023 Symptoms ...

MSA is divided into MSA-C (cerebellar type) which has more symptoms of ataxia (incoordination) and MSA-P (parkinsonian type) which has more parkinsonian symptoms but is relatively unresponsive to the ...

The Food and Drug Administration has granted Orphan Drug designation to PBT434 (Prana Biotechnology), an investigational agent for the treatment of multiple system atrophy (MSA).

People with multiple system atrophy (MSA) generally have a very poor prognosis. Their median survival is 6.2 to 9.5 years after the first symptoms appear. Patients who are older at the time of ...