Visual rating scales allow atrophy of medial temporal lobe structures to be categorized into discrete levels of increasing severity. Structures with definite boundaries can be labeled by manual ...

Risk factors for prestroke dementia (and, hence, poststroke dementia) included medial temporal lobe atrophy, female sex and a family history of dementia. The occurrence of multiple strokes ...

LATE-NC diagnostic criteria improve differentiation from Alzheimer's, addressing challenges in memory-loss syndromes and guiding therapeutic interventions.

Kuzniecky et al. expressed concerns about the differences between normal aging-related cerebral atrophy observed in our healthy controls and those reported in a previous study, which showed ...

Systemic lupus erythematosus (SLE) often presents with neuropsychiatric (NP) involvement, including cognitive impairment and depression. Past magnetic resonance imaging (MRI) research in SLE patients ...

More information: Arunima Kapoor et al, Association of Medial Temporal Lobe Cerebrovascular Reactivity and Memory Function in Older Adults With and Without Cognitive Impairment, Neurology (2025).

A normal MRI brain, showing no atrophy, depicts the three areas of interest in the brain's medial temporal lobe: hippocampus (outlined in red); entorhinal cortex (blue) and perirhinal cortex (green).

However, the precise contribution of periventricular hyperintensities (PVH), deep white matter hyperintensities (DWMH), and medial temporal lobe atrophy (MTA) to task performance remains unspecified.