In work published in Nature Biotechnology, Rubin and his research group turned to 3D cell culture to take on the problem of generating sufficient satellite cells for regenerative therapies. 2 ...

Muscle-on-chip systems are three-dimensional human muscle cell bundles cultured on collagen scaffolds. A Stanford University research team sent some of these systems to the International Space Station ...

Aging muscles heal more slowly after injury—a frustrating reality familiar to many older adults. A UCLA study conducted in mice reveals an unexpected cause: Stem cells in aged muscle accumulate higher ...

Muscle stem cells repurpose the tenogenic factor Scx to establish a muscle-specific transcriptional program that sustains stem cell expansion, migration, differentiation, fusion, self-renewal, and ...

Muscles are formed by the merging of many small myoblasts into larger myofibers. This fusion of mononucleated myoblasts with a single nucleus into multinucleated myofibers with multiple nuclei is an ...

When bones break and there is extreme tissue loss--such as after a car accident or a battlefield injury--current treatments don't often lead to effective healing. But certain stem cells from skeletal ...

Skeletal muscle and cardiovascular diseases continue to pose significant challenges to public health, affecting a wide range ...

As muscles age, their cells lose the ability to regenerate and heal after injury. Now, Cornell University researchers have created the most comprehensive portrait to date of how that change, in mice, ...

- Muscle cells, also known as myocytes, are specialized cells designed for contraction and force production. Skeletal Muscle Cells: These cells are long, cylindrical, and have a striated (or striped) ...