Long non-coding RNAs (lncRNAs) are RNA transcripts longer than 200 nucleotides that do not code for proteins. Once considered mere transcriptional noise, lncRNAs are now known to play vital roles in ...
A new review published in Genes & Diseases explores the intricate epigenetic regulatory network of long noncoding RNAs (lncRNAs) in hepatocellular carcinoma (HCC), shedding light on the profound ...
At the onset of diabetic cardiomyopathy, Trdn-as expression increases, which regulates the methylation of Casq2 mRNA mediated by METTL14, thus increasing the stability and expression of Casq2 mRNA.
Epigenetics, the study of changes in gene function that do not involve alterations to the DNA sequence, plays a pivotal role in understanding the complex interplay between genetics and the environment ...
Cover -- Title Page -- Copyright Page -- Dedication -- Contents -- About the Editors -- List of Contributors -- Preface -- Acknowledgments -- Part I Theoretical and ...
Our genes contain all the instructions our body needs to function, but their expression must be finely regulated to guarantee that each cell performs its role optimally. This is where DNA and RNA ...
Diet can leave lasting epigenetic marks that reshape gene expression, metabolic pathways, and disease susceptibility across the lifespan. These diet-driven molecular changes may create a form of ...