The nucleolus—a conspicuous but obscure organelle within the cell nucleus—is normally too compact to be studied in detail. Researchers at Case Western Reserve University just learned how to simplify ...
Biologists discovered that a scaffolding protein called TCOF1 is responsible for the formation of a biomolecular condensate called the fibrillar center, which forms within the cell nucleolus. Inside ...
At most, 10 people in the world are known to have BPTA. Five of them participated in the current study, and they were found to share virtually the same mutation in the gene for the HMGB1 protein. It ...
Deep within the nucleus of every cell lies a structure smaller than a pinpoint that may hold the secret to aging. Scientists at Weill Cornell Medicine have discovered that the nucleolus, long known ...
The secret to cellular youth may depend on keeping the nucleolus—a condensed structure inside the nucleus of a cell—small, according to Weill Cornell Medicine investigators. The findings were ...
The secret to cellular youth may depend on keeping the nucleolus -- a condensed structure inside the nucleus of a cell -- small, according to nvestigators. The findings were elucidated in yeast, a ...
THE nucleolus was first figured in 1781 as a spot in the centre of a round or oval body (the nucleus) in epithelial cells of the eel. Since then it has been described in the nuclei of almost every ...
IT is true, as Miss Melland states, that the nucleolus as it grows can interfere mechanically with the structure of a chromosome. It can, for example, stretch the filament which connects the satellite ...
Inside all living cells, loosely formed assemblies known as biomolecular condensates perform many critical functions. However, it is not well understood how proteins and other biomolecules come ...
This model of the nucleus with nucleolus (pink) shows how ribosomal DNA is correctly repaired in young cells. In old cells with enlarged nucleolus, however, DNA repair is inaccurate leading to faster ...