What makes us human? According to neurobiologists it is our neocortex. This outer layer of the brain is rich in neurons and lets us do abstract thinking, create art, and speak complex languages. An ...

Organoids, formed as intricate three-dimensional (3D) structures, hold the capacity to originate from a wide array of cellular sources, ranging from embryonic stem cells (ESCs) and induced pluripotent ...

For over a decade, scientists have been growing organoids — small clusters of cells that mimic a particular organ — to serve as miniature biological models. Organoids of the brain have been used to ...

Image of pancreatic organoids under a microscope with immunofluorescent staining. While growing organoids from highly proliferative tissues, such as the stomach and liver, is relatively easy, ...

A new genetic screening method allows researchers to efficiently modulate individual genes across entire tissues and provides ...

Dr. Angels Almenar-Queralt is Assistant Professor, Department of Pediatrics at the University of California, San Diego. The organoid field has come a long way in a relatively short amount of time. The ...

In a breakthrough for bioengineering, researchers have developed organoids that can model the human respiratory tract. The organoids, called AirGels, allow them to uncover the mechanism by which ...

Organoids are three-dimensional, miniaturized, and simplified versions of organs produced in vitro from stem cells or organ-specific progenitor cells. They recapitulate key structural and functional ...

Sometimes hundreds of thousands of potential therapeutics need to be tested in large-scale, fully automated experiments to identify a single effective drug. Most compounds do not work as desired, and ...

In a recent review published in the journal Organoids, scientists have presented an overview on the use of human stem cell-derived organoids in understanding functionality and cellular tropism of ...