This new article publication from Acta Pharmaceutica Sinica B, discusses how palmitoylation of Tfr1 enhances platelet ferroptosis and liver injury in heat stroke. Tfr1 palmitoylation-mediated ...

Pyrrolizidine alkaloids (PAs), widely distributed in plants, are known to induce liver failure. Hepatic platelet accumulation has been reported during the progression of PA-induced liver injury ...

Megakaryocytes, which are derived from hematopoietic stem cell precursors in bone marrow, form and release platelets; these circulate in the blood for 8 to 10 days before they are removed by hepatic ...

When most people think about liver disease, they think about alcohol or hepatitis. What many don’t realize is that the most common cause of chronic liver disease in the United States today has nothing ...

Immune thrombocytopenia (ITP), previously called idiopathic thrombocytopenic purpura, is a rare blood disorder where your body’s immune system attacks and destroys your platelets. Platelets help form ...

Chronic liver disease gets worse when the liver's immune system stays overactive, resulting in ongoing inflammation and scarring. Signals from the gut make the situation worse by encouraging immune ...

What Is Doptelet, and Why Does It Matter? Doptelet (avatrombopag) is a prescription medicine that helps the body make more platelets (cells that help stop bleeding). First approved in 2018 for adults, ...

Could liver problems cause these symptoms? Some of the early symptoms of liver disease are persistent tiredness, reduced ...

Background Metabolic-associated steatotic liver disease (MASLD) is a prevalent chronic liver disease affecting approximately ...