Post-translational modifications (PTMs) are enzymatic, covalent chemical modifications that dynamically regulate protein function and cellular signalling by increasing the functional diversity of the ...

Protein crotonylation is a non-acetylated modification discovered with the development of mass spectrometry. The crotonylation involves many physiological processes, and abnormal crotonylation is ...

DOMEK is a multi-step pipeline which leverages mRNA display-derived next-generation sequencing data to derive kinetic information about substrates of post-translational modification enzymes.

Lactylation, a recently identified post-translational modification, has emerged as important for immune regulation, tissue repair, cancer cell metabolism, and now, potentially, Alzheimer’s disease. In ...

A pharmaceutical scientist at the National University of Singapore (NUS) has developed a method that can measure the kinetic efficiency of an enzyme against more than 200,000 potential peptide ...

A molecular model showing three of the main epigenetic modifications of DNA (orange) and histones (dark blue) [JUAN GAERTNER/Science Photo Library/Getty Images] Post-translational modifications (PTMs) ...

Respiratory infections, pink eye, or an upset stomach may seem like unrelated, mild inconveniences, but all of these ailments share one root cause: adenovirus infection. Many of us will encounter some ...

Protein palmitoylation is a post-translational modification catalyzed by a series of enzymes called zinc finger DHHC (ZDHHC) palmitoyltransferases. Scientists from Guangzhou Medical University and ...