Eyam Health Inc. today announced the publication of peer-reviewed research in Nature Communications describing Gemini™, a binary self-amplifying genetic expression platform that can be deployed as ...

Measuring DLL3 expression via circulating tumor cells (CTCs) may help predict which patients with ES-SCLC will respond to tarlatamab.

This article and associated images are based on a poster originally authored by Marina Fedorova and Ian Hiles and presented at ELRIG Drug Discovery 2024 in affiliation with GSK. This poster is being ...

The search space for protein engineering grows exponentially with complexity. A protein of just 100 amino acids has 20100 ...

The cost-effective, easy-to-use T7 expression system has been integral to Escherichia coli protein production since its introduction in 1986. Now, a just-developed enhancement is making it even better ...

Membrane proteins are the gateway to cells and are involved in many critical functions. Each membrane protein is unique, and their complexity makes it difficult to fit into a standardized expression ...

The search space for protein engineering grows exponentially with complexity. A protein of just 100 amino acids has 20^100 possible variants-more combinations than atoms in the observable universe.

Carfilzomib prevented BCMA degradation, increased target density, and improved CAR T susceptibility by ~26%–28% in vitro, while enhancing xenograft antitumor activity without worsening T-cell ...

To enhance CAR T therapies, scientists are actively studying TCR signaling and T-cell exhaustion mechanisms to improve CAR T persistence and function. Additionally, there is a growing trend towards ...

Researchers identified three age-related proteins that may play key roles in PH progression as possible treatment targets.