Biohub today announced the release of a world model of protein biology: a scientific engine for prediction, design, and ...

A new LMU study shows how proteins function reliably even without a stable 3D structure – and the crucial importance not only of short sequence motifs, but also of the chemical characteristics. Many ...

On Wednesday, the Nobel Committee announced that it had awarded the Nobel Prize in chemistry to researchers who pioneered major breakthroughs in computational chemistry. These include two researchers ...

In synthetic and structural biology, advances in artificial intelligence have led to an explosion of designing new proteins with specific functions, from antibodies to blood clotting agents, by using ...

Proteins systematically lose their protective hydration shell when their environment becomes more acidic. Until recently, ...

This year’s Lasker Basic Medical Research Award recognizes the contributions of Demis Hassabis and John Jumper for their invention of the AlphaFold artificial intelligence (AI) system, which predicts ...

This fully updated volume explores a wide array of new and state-of-the-art tools and resources for protein function prediction. Beginning with in-depth overviews of essential underlying computational ...

For most proteins, structure is function. The complex three-dimensional shapes that proteins adopt create folds and pockets that can accomplish the remarkably improbable: driving chemical reactions ...

Peptides have gradually emerged as some of the most intriguing molecular tools in contemporary biochemical research. Their constructional versatility, small size, and potential to interact with highly ...

In genetics, one harmful variant can be enough to cause disease—but two can make it far more severe. One notable example is KJ, an infant diagnosed with a rare urea cycle disorder with a grim ...