National Institutes of Health (NIH) researchers and collaborators have found that being a carrier for sickle cell disease, known as having sickle cell trait, increases the risk of blood clots, a risk ...

Gene therapy for sickle cell disease may help improve a major contributing factor to stroke risk in patients, reports a new study from St. Jude Children's Research Hospital. Many people with sickle ...

GLP-1 receptor agonist use appeared linked to significantly reduced all-cause mortality among people with sickle cell disease ...

Children with sickle cell disease, a chronic hemolytic anemia, present with a wide variety of neurological syndromes, including ischemic and hemorrhagic stroke, transient ischemic attacks, 'soft ...

Africa accounts for the majority of global births affected by the condition, yet universal newborn screening remains rare.

Large European cohort data suggest hydroxyurea pregnancy exposure in sickle cell disease is not linked to congenital malformations, supporting nuanced clinical decision-making.

Avascular necrosis is the breakdown and death of bone tissue due to insufficient blood supply. It’s a common complication of sickle cell disease, but early diagnosis and treatment can help slow ...

Sickle cell disease (SCD) can affect people of any ethnicity but is much more common among Africans and African Americans. Other ethnic groups with higher rates of SCD include Hispanic Americans from ...