By disrupting both the physical and biochemical cues that promote fibrotic remodeling—selectively in stromal cells—this dual approach offers a promising blueprint for future "mechanotherapies" aimed ...
Fig 1. WSI-based fibrosis assessment. (A) Schematic illustration of manual annotations for 8 distinct tissue classes in whole-slide image. (B) Development of tissue classification models and ...
Most pancreatic tumors are surrounded by a thick, nearly impenetrable wall of fibrosis— scar tissue—that makes it hard for drugs to access and destroy the cancer cells. Researchers at the Salk ...
On October 3, 2025, a multicenter team from Shenzhen University, Xiangya Hospital of Central South University, Zhujiang Hospital of Southern Medical University, Wuxi People's Hospital Affiliated to ...