Medscape

Warfarin, Sulfonylurea Combo Ups Severe Hypoglycemia Risk

Concurrent use of warfarin and the diabetes drugs glipizide and glimepiride appears to dramatically elevate the risk for severe hypoglycemia in older adults, a new analysis shows. The findings, from a ...
TCTMD

Glipizide, Commonly Used Sulfonylurea, Linked to Greater CV Risks

Moderate-risk patients with diabetes treated with a sulfonylurea appear to be at a higher risk of major adverse cardiovascular events than those who receive a dipeptidyl peptidase-4 (DPP-4) inhibitor, ...
MedPage Today

Hypoglycemia: 5-Fold Greater Risk in Sulfonylurea Users With Renal Impairment

Type 2 diabetic (T2D) patients taking sulfonylureas are at an increased risk of hypoglycemia (2.5x) compared to metformin users. T2D patients taking sulfonylureas with severe renal impairment (GFR 30 ...
Healio

Sulfonylurea-related hypoglycemia may lead to negative cardiac effects

Please provide your email address to receive an email when new articles are posted on . In adults with type 2 diabetes treated with a sulfonylurea, asymptomatic hypoglycemic episodes are common and ...
Medscape

Switching From Metformin to Sulfonylurea Raises CV Risks

Switching therapy from metformin to a sulfonylurea increases the risk for adverse outcomes in patients with type 2 diabetes, new research suggests. Results of a study using data from the UK Clinical ...
The American Journal of Managed Care

Swapping Metformin for Sulfonylureas Boosts CV Risk in Type 2 Diabetes, Study Finds

Sulfonylureas are an older class of type 2 diabetes therapy but remain the most commonly prescribed antidiabetic drug after metformin. Patients taking metformin for type 2 diabetes (T2D) who switch to ...
FiercePharma

In a Post-Hoc Analysis, JANUVIA® (sitagliptin), Merck’s Diabetes Medicine, Compared with a Sulfonylurea (Glipizide)

WHITEHOUSE STATION, N.J.--(BUSINESS WIRE)-- In a new post-hoc analysis presented for the first time at the American Diabetes Association (ADA) 70 th Annual Scientific Sessions, significantly more ...
Monthly Prescribing Reference

Combining Sulfonylureas with These Cholesterol Drugs May Up Severe Hypoglycemia Risk

Heart Failure and LUTS: Managing Competing Drugs A new study has highlighted the risk of delayed severe hypoglycemia with concomitant sulfonylurea (SU) and fibrate use. A new study has highlighted the ...
FiercePharma

In two additional presentations, linagliptin demonstrated hemoglobin A1c reductions in patients with mild, moderate or severe renal impairment

SAN DIEGO, June 24, 2011 /PRNewswire/ -- Boehringer Ingelheim and Eli Lilly and Company (NYSE: LLY) today announce Phase III study results for linagliptin, demonstrating improved glycemic control in ...
The New England Journal of Medicine

Long-Term Experience with Sulfonylureas and Placebo

THE sulfonylurea compounds have been employed widely in the treatment of diabetes mellitus since their introduction in the mid-1950's, and large series are now available outlining the effectiveness, ...
Business Wire

Merck Receives Complete Response Letter from the U.S. FDA for TECOS Study with Sitagliptin

Hypoglycemia does not occur in patients receiving metformin alone under usual circumstances of use, but could occur when caloric intake is deficient, when strenuous exercise is not compensated by ...