Adolescence is widely thought to be a time when the brain trims away excess neural connections, refining circuits through synaptic pruning. New research now suggests this view may be incomplete.

A new study on the detriments of too many synaptic connections in the mouse cerebellum by neuroscientists at the Washington University School of Medicine in St. Louis corroborates previous human ...

Researchers developed SynTrogo, a molecular tool enabling targeted synapse removal via engineered neuron–astrocyte ...

Subscribe to our newsletter for the latest sci-tech news updates. Despite these developments, most widely employed methods to image synaptic connectivity are slow and fail to precisely record changes ...

Neuronal Type Assignment from Connectivity (NTAC) transforms a connectome into a graph, and detects neuron types using "connectivity fingerprints” and groups the neuronal cell types in the connectome.

This original animation illustrates that presynaptic neurons secrete VLK, which then phosphorylates the extracellular side of ephrin type-B receptor 2 (EphB2) extruding from the membranes of ...

On this Freedom Day, explore how the Synaptome Project redefines our understanding of trauma and resilience, revealing the ...

This valuable study presents a plastic recurrent spiking network model that spontaneously generates repeating neuronal sequences under unstructured inputs. The authors provide solid evidence that, ...