Primordial germ cells (PGCs) migrate to the developing gonads and proliferate. Gonadal somatic cells differentiate into ovarian stroma, granulosa, and theca cells.

Batalha IM, Maylem ERS, Spicer LJ, Pena Bello CA, Archilia EC, Schütz LF. Effects of follicle-stimulating hormone, insulin-like growth factor 1, fibroblast growth factor 2, and fibroblast growth ...

In a couple days the theca cells enveloped the granulosa and eggs, mimicking a real ovary. The big test, however, was whether the structure could function like an ovary — namely to mature eggs.

The origin of the ovarian follicle's theca cells has been determined, and the molecular pathways contributing to egg maturation have been clarified. genprowebdirectory ...

Inside follicles, they found not only oocytes, but also theca and granulosa cells, two types of hormone-secreting cells that surround the immature eggs. By digging into these cells’ gene expression ...

"Aged epithelial cells exhibited significantly elevated expression of cell-cycle-associated genes, whereas aged granulosa cells, theca cells, and endothelial cells showed increased expression of ...

Granulosa-theca cell tumors arise from the granulosa and theca cells of the ovarian follicle and are regarded as sex cord stromal tumors. They vary in the proportion of each type of cell present.

Production of insulin-like growth factor-I by granulosa cells but not thecal cells is hormonally responsive in cattle. J Anim Sci 2000; 78:2919–26.

Whole Genome Transcriptomic Analysis of Ovary Granulosa Cells Revealed an Anti-Apoptosis Regulatory Gene DLGAP5 in Polycystic Ovary Syndrome, Frontiers in Endocrinology, 13, (2022). https://doi ...

Two cells that are important for estrogen production, theca and granulosa cells, were removed from rats and encapsulated. These ovarian constructs were implanted in rats that had their ovaries removed ...