Scientists have discovered how two transcription factors form a reciprocal regulatory circuit that controls T-cell exhaustion and migration during viral infection, which may inform future therapeutic ...

"New technique reveals how gene transcription is coordinated in cells." ScienceDaily. www.sciencedaily.com / releases / 2024 / 06 / 240605162356.htm (accessed August 31, 2026).

The human genome contains about 23,000 genes, but only a fraction of those genes are turned on inside a cell at any given time. The complex network of regulatory elements that controls gene expression ...

A cell protein previously believed only to provide a scaffolding for DNA has also been shown to directly influence DNA transcription into RNA – the first step of the process by which an organism's ...

A new study has uncovered new genetic rules that determine how CD8 “killer” T cells choose between becoming long-lasting, protective immune cells or slipping into exhausted, dysfunctional states.

Transcription factors (TFs) are proteins that bind to specific DNA sequences, regulating the transcription of genetic information from DNA to messenger RNA (mRNA). These proteins play a pivotal role ...

Researchers from the A*STAR Institute of Molecular and Cell Biology (IMCB) have identified Nr1h2, a critical transcription factor essential for early embryo development. Published in Nature ...