Traffic is severely backed up in the southbound lanes of I-81 in Franklin County due to a crash in Washington County, Md.

A disabled tractor-trailer caused severe delays on Interstate 81 in Dauphin County, according to PennDOT. Video above: ...

A Hagerstown, Md., man faces charges after a woman's 911 call claiming kidnapping led to police tracking down a Toyota Rav 4 ...

A tractor-trailer accident on Interstate 81 on Monday prompted hazmat teams to clear the scene before anyone could drive through the area again safely.

Four teens on a crime spree were headed to Connecticut but drew the attention of PSP after pointing a gun at another motorist ...

State Police say Manuel De Jesus Ascencio Castro, 32, led police on a high-speed chase on the highway with a woman and three ...

Police closed the Main Avenue exit and on-ramps for I-81 South after a pedestrian was struck Wednesday morning.

TROOPERS SAY THEY WERE CALLED TO THE CARLISLE, MECHANICSBURG AREA OF INTERSTATE 81 FOR A PASSENGER IN A RED TOYOTA TUNDRA PICKUP TRUCK POINTING A GUN AT OTHER DRIVERS. AROUND 1230 YESTERDAY AFTERNOON.

Cortland County, N.Y. — Interstate 81 north bound is closed to all traffic at Exit 54 (Cortland/Homer) after multiple crashes ...

A pickup truck was traveling south on Interstate 81. The driver lost control and the truck went off the road, through a guide ...

GREENVILLE — Portions of Interstate 81 were closed Monday for several hours in Augusta County following the crash of a tanker-truck that was carrying ammonia, authorities said. VDOT reported all ...