Please provide your email address to receive an email when new articles are posted on . “There are no clear data to suggest that allopurinol is detrimental to renal function in patients with gout,” ...

gout of foot The investigational drug AR882 appeared more effective and safer than allopurinol monotherapy in a phase 2 trial. A novel selective URAT1 inhibitor, AR882, further reduces serum uric acid ...

Trial subgroup analyses support the use of either allopurinol or febuxostat in patients with stage 3 CKD and gout. A prespecified analysis of the STOP-GOUT trial revealed that allopurinol has similar ...

Arhalofenate (800mg) is safe and significantly decreases gout flares compared to allopurinol (300mg), according to a study published online July 27 in Arthritis & Rheumatology. HealthDay News — ...

The effects of allopurinol treatment on mortality among patients with gout remain uncertain, with a new meta-analysis finding conflicting results. In a systematic review of the literature that ...

December 16, 2011 — A retrospective analysis of data from 222 hyperuricemic women with gout who had participated in phase 3 comparative trials showed that febuxostat, 80 mg/d, was more effective than ...

Allopurinol (Alpuric) is prescribed to treat gouty arthritis and prevent specific kidney stones by reducing high uric acid levels in the blood. Allopurinol (Alpuric) is a xanthine oxidase inhibitor, ...

Chicago, IL - Results of a phase 3, randomized, double-blind study show that febuxostat (TAP Pharmaceutical Products) is more effective in lowering serum uric acid than the current standard of care, ...

Allopurinol (4-hydroxypyrazolo-(3, 4-d) pyrimidine, HPP), a xanthine oxidase inhibitor, offers a new concept in the prevention of the complications of hyperuricemia. By effectively blocking the ...

Initiating allopurinol during an acute gout attack doesn't adversely affect the resolution of the attack, according to results of a new placebo-controlled, double-blind study. Allopurinol given during ...

BACKGROUND: Allopurinol is commonly prescribed for gout, and its clinical use may expand with ongoing trials assessing its potential cardiorenal benefits. Because heart disease has been suggested to ...

Severe anemia and myelosuppression are rare but serious complications of azathioprine that are more likely to occur at high doses or when potentiated by interactions with other drugs. Xanthine oxidase ...