A new type of tissue model that more accurately mimics the architecture of the liver could help develop drugs to treat MASLD.

In a new study, researchers from Institute of Science Tokyo, Japan, have utilized bile acids as farnesoid X receptor agonists to develop unique hepatic organoids that are capable of sustained, ...

Cellular senescence is marked by irreversible cell cycle arrest, lysosomal changes, regulatory protein expression, and SASP activation, impacting tissue health and repair. Cellular senescence is a ...

A high-fat diet does more than overload the liver with fat. New research from MIT shows that prolonged exposure to fatty foods can push liver cells into a survival mode that quietly raises the risk of ...