Brandon Aiyuk caught four passes for 43 yards in the San Francisco 49ers' Week 2 loss to the Minnesota Vikings. While it may ...

The San Francisco 49ers are preparing for their Week 3 contest against the Los Angeles Rams on Sunday at SoFi Stadium in ...

San Francisco 49ers defensive coordinator Nick Sorensen, offensive line/run game coordinator Chris Foerster, and quarterback ...

The San Francisco 49ers will be without a couple of key players Sunday, but their troubles pale in comparison with the ...

The 49ers added tight end George Kittle (hamstring), cornerback Charvarius Ward (hamstring/knee) and edge rusher Nick Bosa ...

George Kittle and Charvarius Ward not practicing Thursday could mean the San Francisco 49ers will be missing four All-Pros ...

San Francisco 49ers safety Talanoa Hufanga is poised to make his season debut on Sunday against the Los Angeles Rams.

San Francisco 49ers quarterback Brock Purdy isn't letting early-season injuries shake his confidence. Although he has been ...

Football, they say, is a war of attrition. For the 49ers and the Rams, attrition has arrived with a capital A.The latest name ...

San Francisco 49ers running back Christian McCaffrey will practice on Wednesday, though he will once again be limited.

The San Francisco 49ers will be missing two of their biggest playmakers when they visit SoFi Stadium on Sunday to face the ...

There's no panic in the San Francisco 49ers locker room despite recent injuries and a disappointing Week 2 loss to the ...