AI has advanced molecule design, yet synthetic feasibility remains a bottleneck. Chemistry-first approaches offer a practical ...

Explore the impact of lysosomal lipid recycling in a rare multi-organ disorder linked to the SPNS1 gene mutations.

A breakthrough study reveals a new antibody that could transform the fight against HIV, neutralising over 98 percent of ...

Explore the challenges of CNS drug development for neurodegenerative diseases and the complexity of measuring disease ...

Scientists have linked rare mutations in SPNS1 to a previously unknown lipid recycling pathway in lysosomes, revealing how faulty fat processing can trigger muscle and liver disease.

New research has discovered how Rab proteins control the delivery of critical supplies to strengthen neural connections, providing researchers with important insights into memory formation and ...

Researchers have developed bioactive nanoparticles that restore the brain’s blood-brain barrier and clear toxic proteins, reversing Alzheimer’s symptoms in mice and offering a promising new approach ...

Drug discovery now costs 100 times more per FDA-approved drug than in 1950, despite vast advances in biology and computing. The core problem is the collapse of predictive validity in preclinical ...

CRISPR therapies depend on delivery and lipid nanoparticles are emerging as a more flexible and scalable option than viral vectors. Gene editing through clustered regularly interspaced short ...

14 October 2025 | By Dr Jack Scannell (CEO of Etheros Pharmaceuticals Corp), Dr Raminderpal Singh (Hitchhikers AI and 20/15 Visioneers) Drug discovery now costs 100 times more per FDA-approved drug ...