Androgen biosynthesis in the human fetus proceeds through the adrenal sex steroid precursor dehydroepiandrosterone, which is converted to testosterone in the gonads, followed by further activation to ...
Fetal adrenal cells are critical for the establishment of the capsular–cortical unit of the adrenal gland; these cells populate the mesenchymal capsule to become stem cells for the underlying adult ...
Adrenal androgens, primarily dehydroepiandrosterone (DHEA) and its sulphate (DHEAS), have long been recognised as key precursors in steroid metabolism. More recently, the identification of ...
New research by academics at the University of Bristol has found evidence that prolonged treatment of synthetic corticosteroid drugs increases adrenal gland inflammation in response to bacterial ...
Regensburg, Germany - The reduced levels of cortisol and adrenal androgens seen in patients with rheumatoid arthritis (RA) or systemic lupus erythematosus (SLE) are not due to increased renal ...
Cultured adrenal tumor cells respond to adrenocorticotropin (ACTH), adenosine 3',5'-cyclic monophosphate (cAMP), cholera enterotoxin (CT), and Escherichia coli enterotoxin with increased ...
Expert Rev Endocrinol Metab. 2012;7(5):555-566. To summarize, all available studies support the possibility that the HPA axis response to neuroendocrine stimuli may be altered only in a subset of ...
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