Androgen biosynthesis in the human fetus proceeds through the adrenal sex steroid precursor dehydroepiandrosterone, which is converted to testosterone in the gonads, followed by further activation to ...

Share on Facebook. Opens in a new tab or window Share on X. Opens in a new tab or window Share on LinkedIn. Opens in a new tab or window BOSTON -- Investigational crinecerfont reduced the need for ...

What are the Causes of Congenital Adrenal Hyperplasia (CAH)? Congenital Adrenal Hyperplasia (CAH) is caused by the deficiency of steroid hormone synthesizing enzymes, which occur due to mutations in ...

Credit: Shutterstock. Crinecerfort is an investigational, oral, selective corticotropin-releasing factor type 1 receptor (CRF1) antagonist. A phase 3 study evaluating the efficacy and safety of ...

Spruce Biosciences Presents Phase 2 Data for Tildacerfont in Adults with Congenital Adrenal Hyperplasia at 23rd European Congress of Endocrinology Richard Auchus, MD, PhD, Presents Phase 2 Data of ...

Citation: Stewart S (2013) Rare diseases 5: treating congenital adrenal hyperplasia. Nursing Times; 109: 49/50, 23. Author: Sue Stewart is clinical nurse specialist in endocrinology and genetics at ...

Steroid biosynthesis is affected in the AR disorder known as congenital adrenal hyperplasia (CAH): the majority of cases are due to 21-hydroxylase deficiency. Androgen excess affects women’s ...

For the first time, mice with a faulty human gene responsible for a rare genetic illness called congenital adrenal hyperplasia have been created. The discovery, presented at the 25th European Congress ...

Congenital adrenal hyperplasia (CAH) represents a group of inherited disorders resulting from enzyme deficiencies that disrupt the synthesis of adrenal steroid hormones. One notable form, caused by ...

SAN DIEGO, May 15, 2025 /PRNewswire/ -- Neurocrine Biosciences, Inc. (Nasdaq: NBIX) today announced new data from the Phase 3 CAHtalyst™ Adult and Pediatric studies of CRENESSITY™ (crinecerfont). The ...

This article is based on research findings that are yet to be peer-reviewed. Results are therefore regarded as preliminary and should be interpreted as such. Find out about the role of the peer review ...

Nonclassical congenital adrenal hyperplasia (NCAH) can lead to the production of excess male hormones. It is usually a mild condition and often doesn’t need to be treated. Nonclassical congenital ...