Preclinical study showed PDIA1 and PDIA5 protect cells from oxidative stress, maintain mitochondrial function, and are involved in androgen receptor regulation.

Researchers have discovered how sperm cells perform an extraordinary metabolic transformation after ejaculation, from quiet ...

Results from the largest cohort of children who received a gene therapy for a rare immunodeficiency condition have shown the ...

Nine-year-old Andy Cash was diagnosed with Adenosine deaminase-deficient severe combined immunodeficiency (ADA-SCID), a rare ...

Scientists have found a key weakness in prostate cancer cells. Two enzymes, PDIA1 and PDIA5, help cancer cells survive and ...

An experimental gene therapy developed by researchers at UCLA, University College London and Great Ormond Street Hospital has ...

Researchers convert type A kidney to type O, potentially reducing wait times and saving lives. Experimental gene therapy ...

Aldolase fuels sperm with glucose for the final sprint to the egg. Inhibiting this enzyme can be an efficient approach for ...

Aicuris has reported the success of a phase 3 trial, which has demonstrated the superiority of oral antiviral pritelivir ...

The proportion of people with heart failure receiving optimal therapy increased significantly with expansion of this ...

By targeting a newly uncovered weakness in prostate cancer cells, this could offer an improved treatment for the disease.