Patients with Klinefelter and triple X syndromes show an increased prevalence of SLE and Sjögren disease, likely due to the synergistic interaction of the extra X chromosomes.

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Karyotyping performed by G-banding technique revealed a 47 XXY karyotype, which is diagnostic of Klinefelter's syndrome. Doppler ultrasound of the leg ulcers disclosed partial thrombus in the ...

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In addition, sex chromosomal abnormalities like Turner syndrome and Klinefelter syndrome may have an effect on physical and reproductive development. While some defects are inherited, many are ...

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(Circulation: Cardiovascular Imaging) Men with Klinefelter syndrome did not appear to show cardiovascular side effects from testosterone replacement therapy in a retrospective study. (Lancet ...

Another example, 47,XXY syndrome, also known as Klinefelter syndrome, is linked to infertility and underdeveloped, poorly functioning testes, among other symptoms, said Reiches. “Biologists tend ...