Background Current treatments with tyrosine kinase inhibitors and immune checkpoint inhibitors have limited efficacy for ...

The treatment of long benign oesophageal strictures remains a clinical challenge. We present a novel endoscopic technique ...

Background and aims Quantifying systemic inflammation (SI) in acutely decompensated cirrhosis (ADC) is of major importance ...

Background Endoscopic procedures are a notable source of medical waste, contributing significantly to environmental pollution ...

We thank Dr Yang and colleagues for their interest in the HELIOS trial and their thoughtful appraisal of our findings.1 2 Yang et al highlight the possibility that heterogeneity in endoscopist ...

Correspondence to Professor Nigel W Bunnett, Department of Molecular Pathobiology, New York University College of Dentistry, New York, NY 10010, USA; nwb2{at}nyu.edu Objective The effectiveness of ...

4 Department of Pharmacology and Toxicology, Raymond Poincaré Hospital, AP-HP, Garches; Centre for Research in Epidemiology and Population Health (CESP), Team MOODS, Inserm UMRS 1018, ...

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Objective Mitochondrial dysfunction plays a dominant role in the pathogenesis of alcoholic liver disease (ALD); however, the underlying mechanisms remain to be fully understood. We previously found ...

Mounting evidence underscores the pivotal role of the intestinal barrier and its convoluted network with diet and intestinal microbiome in the pathogenesis of inflammatory bowel disease (IBD) and ...

Objective Patients with increased PD-L1 + host cells in tumours are more potent to benefit from antiprogrammed death-1/programmed death ligand-1 (PD-L1) treatment, but the underlying mechanism is ...

Correspondence to Dr Katja Breitkopf-Heinlein, Department of Surgery, University Medical Center Mannheim, Medical Faculty Mannheim, Heidelberg University, 68167 Mannheim, Germany; ...