Researchers have discovered an enzyme, PapB, that can ‘tie off’ therapeutic peptides into stable rings, which could help ...

Learn how accelerating drug discovery is reshaping the pathway from lab findings to effective therapies with real-world data.

A new human liver organoid platform could help predict which drugs trigger dangerous immune reactions in susceptible patients ...

A breakthrough study reveals a new antibody that could transform the fight against HIV, neutralising over 98 percent of ...

AI has advanced molecule design, yet synthetic feasibility remains a bottleneck. Chemistry-first approaches offer a practical ...

Explore the impact of lysosomal lipid recycling in a rare multi-organ disorder linked to the SPNS1 gene mutations.

Explore the challenges of CNS drug development for neurodegenerative diseases and the complexity of measuring disease ...

Drug discovery now costs 100 times more per FDA-approved drug than in 1950, despite vast advances in biology and computing. The core problem is the collapse of predictive validity in preclinical ...

14 October 2025 | By Dr Jack Scannell (CEO of Etheros Pharmaceuticals Corp), Dr Raminderpal Singh (Hitchhikers AI and 20/15 Visioneers) Drug discovery now costs 100 times more per FDA-approved drug ...

New research has demonstrated how tiny tweaks in a DNA-sensing enzyme may hold the key to the naked mole-rat’s extraordinary lifespan – offering insights that could one day inform therapies for aging ...

Researchers have developed bioactive nanoparticles that restore the brain’s blood-brain barrier and clear toxic proteins, reversing Alzheimer’s symptoms in mice and offering a promising new approach ...

The rise of personalised cancer immunotherapy represents a pivotal shift in oncology, aiming to harness the body’s own immune system to recognise and eliminate tumour-specific neoantigens. Encouraging ...