Abstract and Introduction Abstract. Adrenal steroidogenesis is under the control of the hypothalamic–pituitary–adrenal (HPA) axis. Furthermore, metabolic factors including insulin and obesity ...

Bacteria in the urinary tract can convert corticosteroids into androgens, hormones that promote the growth of prostate cancer ...

New research by academics at the University of Bristol has found evidence that prolonged treatment of synthetic corticosteroid drugs increases adrenal gland inflammation in response to bacterial ...

This is an important finding with high clinical relevance as intra-adrenal activation of the immune system can affect adrenal functionality by interfering with the steroidogenic pathway, damaging ...

A research team has unveiled an adrenal independent pathway, the hypothalamus-sympathetic-liver (HSL) axis, to mediate stress-induced glucose release. Their study is published in Nature ...

"Importantly, our research builds on our knowledge of the mechanisms through which corticosteroid drugs induce adrenal insufficiency, by showing simultaneous effects within multiple pathways involved ...

High-fat diet upregulates adrenal steroidogenesis. ... It would be extremely interesting to know what causes Shh pathway activation in adrenal glands of obese animals.

Abstract and Introduction Abstract. Adrenal steroidogenesis is under the control of the hypothalamic–pituitary–adrenal (HPA) axis. Furthermore, metabolic factors including insulin and obesity-related ...

There are sufficient arguments to suggest that insulin excess may be a factor responsible for alteration of adrenal steroidogenesis leading to increased dehydroepiandrosterone sulfate blood levels.