Insulin under normal circumstances exerts its antiatherogenic action in endothelial cells and VSMCs via the PI 3-kinase signaling pathway. Antiatherogenic aspects of insulin action include stimulation ...

A new study focuses on the insulin receptor to understand its role in the development of type 2 diabetes mellitus, a metabolic disease with a major impact on global health. Insulin resistance precedes ...

In this study, we have demonstrated, using two independent normal podocyte cell lines, a previously unsuspected aspect of human podocyte biology: that differentiated podocytes are insulin responsive ...

An international research group has clarified the action mechanism of incretin-based drugs in the treatment of diabetes. The research group headed by Professor SEINO Susumu included Researcher Okechi ...

Tirzepatide is a recently approved treatment for type-2 diabetes. Treatment with tirzepatide decreases body weight while improving glucose metabolism in patients with obesity and type-2 diabetes.

Discover how chromium, a trace nutrient found in whole grains, seafood, and brewer’s yeast, might subtly shape metabolism and ...

On one wall of endocrinologist Kevan Herold’s office hangs artwork by a girl who joined one of his type 1 diabetes trials when she was 11 years old. The girl was diagnosed with stage 2 of the disease, ...

Novel mechanism of action reverses and prevents death of injured cellsPhase II ARPEGGIO trial fully enrolledTopline results to be presented at ...

Insulin resistance is a growing health concern worldwide, linked to a variety of conditions such as type 2 diabetes, polycystic ovary syndrome (PCOS), Alzheimer's disease, metabolic syndrome, and ...

For years, the pancreas has been being taught in biology class as an easy system: insulin lowers blood sugar, and glucagon raises it. But that’s much too simple, new research says.