Objective To confirm that metformin prevents flares in patients with SLE with low disease activity, we performed a post hoc analysis combining our previous two randomised trials.Methods Post hoc ...

Objective: To evaluate the effect of metformin on blood pressure and insulin sensitivity in non-diabetic, moderately obese, hypertensive patients. Patients and Methods: An 8-week double-blind ...

In the earlier, nonobese, Palomba trial it did not exceed 30, with a mean of 27 and 26.7 for metformin and clomiphene, respectively, whereas in their second, more inclusive, trial it ranged from ...

Metformin effects were uniform on the HR scale for all variables, but heterogeneous by age on the absolute (RD) scale, with diabetes incidence rate reduced in the metformin group compared with the ...

Metformin is generally administered at a dosage of 500–2000 mg/day, and the dosage for spironolactone ranges from 25 to 400 mg daily depending upon the specific disease. In order to avoid adverse drug ...

Introduction Impaired glucose tolerance (IGT) is highly prevalent after stroke and is associated with recurrent stroke and unfavourable outcome. Objectives We aimed to assess the feasibility, safety ...

O varian cysts are a common health issue affecting millions of people with ovaries, often going unnoticed and resolving on their own. But in rare cases, they can lead to serious complications.

Introduction Gestational diabetes mellitus (GDM) is a common disorder of pregnancy and contributes to adverse pregnancy outcomes. Metformin is often used for the prevention and management of GDM; ...

Polycystic ovaries: This condition occurs when eggs mature within their sacs but are never released from the ovaries. More and more cysts form and grow, and the ovaries then contain many of these ...

We already know quite a lot about metformin. It's been around for decades, and is considered a gerotherapeutic: a drug able to slow down various aging processes in the body.For example, it's been ...

Oxypurinol is a metabolite of allopurinol, a drug used to treat gout, and metformin is a first-line treatment for type 2 diabetes. Both oxypurinol and metformin enter the wastewater treatment plants ...